Biofez Capsule

– a unique combination of a new generation iron, folic acid and zinc, which stimulates the formation of blood.

Composition of each capsule:

Active ingredients: carbonyl iron – 50 mg (equivalent to 49 mg of iron), folic acid – 500 mcg, zinc sulphate monohydrate – 61.8 mg;

Excipients: maize starch, lactose, sucrose, povidone, Е1201, purified talc Е553, hypromellose Е464, triethyl citrate Е1519, titanium dioxide Е171, erythrosine Е127, iron oxyde Е172, propylene glycol Е1520.


The information on biologically active components and their properties:

Biofez Capsule contains carbonyl iron, which has a number of advantages over other forms of iron, such as:

  • contains about 98% elemental iron
  • easily digested
  • contains salts of iron, and therefore has no side effects on the stomach as constipation and diarrhea
  • safe and non toxic due to the slow dissolution and gradual absorption, under the influence of

gastric acid.  Carbonyl Iron only absorbed at the rate that gastric acid is produced, since gastric acid is

required to make carbonyl iron soluble.1,2

So carbonyl iron:

– An ideal source of pure iron in easily digestible form 3

– A higher content of elemental iron than other forms of Iron4

Source of iron Source of elementary iron
Iron sulfate 20%
Iron gluconate 12%
Carbonyl iron approximately  98%

Iron – the most important microelement which involved in blood formation , respiration, redox reactions and immunological processes.  Extremely important role of iron in the body is determined that takes part of the blood and more than a hundred enzymes. Iron contains in the structure and number of proteins, primarily hemoglobin, which carries oxygen from the lungs to the cells, tissues and organs.

Iron deficiency causes:

  • Blood diseases;
  • Reduced immunity – frequent colds and inflammatory diseases;
  • Violation of the central nervous system – headache, dizziness, insomnia, loss of memory and attention,

flies flashing before my eyes;

  • Cardiovascular disease;
  • Diseases of the digestive tract – chronic gastro, inflammation of the stomach lining;
  • Dry skin and hair, and acne;
  • Inflammation of the mucous membranes of the mouth and nose;
  • Cracks in the corners of the mouth.

Iron deficiency cannot fill using only one diet – there needs to take iron dietary supplements.

Folic acid (vitamin B9)– plays a very important role in the human body. First of all, it is responsible for the process of the production of red blood cells (erythrocytes) and take part in the synthesis of protein in which structure enters iron. A sufficient amount of folic acid in the body ensures normal blood composition, and its quality; normalizes fat and carbon exchange. Insufficient intake of vitamin B9 may cause anemia.

In addition, folic acid is essential for the synthesis of nucleic acids, molecules that contain important genetic information. This vitamin is also very important for growth, development and updating of all cells of the human body.

Folic acid is necessary during pregnancy for its normal flow, fetal growth and development, and health of the woman.

Acceptance of folic acid during pregnancy planning reduces the chances of neural tube birth defects by about 75% .5

With a lack of folic acid observed fatigue, weakness, anemia, diarrhea, weight loss, irritability, depression, weakened memory.

Zinc – an important microelement of the human body, which involved in the synthesis of hemoglobin contained in red blood cells and 6. take part in more than 70 enzymes that catalyze the key stages of synthesis of DNA, RNA and proteins. Has a strong impact on the growth and maturation of tissues.

Zinc deficiency causes many disorders and diseases. Delayed or even stop growth, improperly formed skin; skin dries and becomes vulnerable – can appear ulcers, rashes, eczema. Suffering hair – it becomes liquid and early fall. Affects the brain, and there are nervous and mental diseases. With a shortage of zinc worsens the blood: red blood cells live on less – there is anemia and disturbed coagulation. Reduced immune status, as lymphocytes – immune cells – also becomes smaller.

It is assumed that zinc deficiency during pregnancy can pose a threat to the child’s development and lead to adverse effects during childbirth. A low level of zinc in plasma reduced transplacental transfer of zinc may affect the amount of zinc entering the fetus 7

Indication: Recommending as an additional source of iron, folic acid and zinc to prevent anemia. Also, for women are planning pregnancy and during lactation.

Dosing: 1 capsule per day before meals. Duration of use please consult with your doctor.

It is recommended to consult with your doctor before intake Biofez Capsule.

Do not exceed the daily recommended dose.

 Precautions for use: not recommended to sensitivity of individual components and the children under 12 years. Do not take dietary supplement “Biofez Capsule” in  hemochromatosis, hemosiderosis, or hemolytic anemia.

Interactions: since Biofez Capsule can reduce the absorption of antibiotics (tetracycline and fluoroquinolones), levodopa, methyldopa, levothyroxine penitsallaminu and the interval between doses should not less than 2 hours.

Do not take antacids within 2 hours after taking Biofez Capsule, as they can reduce the absorption of carbonyl iron.

Biofez Capsule not contains GMO.

Storage: Store in original container, out of reach of children, at a temperature below 25 ° C.

Manufacturer :       Jayson Pharmaceuticals Ltd. Dhaka, Bangladesh.

231, Tejgaon industrial area, Dhaka-1208, Bangladesh

1 .Gordeuk VR, Brittenham GM, McLaren CE, Hughes MA, Keating LJ. Carbonyl iron therapy for iron deficiency anemia. Blood. 1986;67(3):745-752. 
2 .Brittenham GM, Klein HG, Kushner JP, Ajioka RS. Preserving the national blood supply. Hematol Am Soc Hematol Educ Program. 2001:422-432.  
3 .Drugs facts and Comparisons 1996, 50th edition 
4 .
5. American Journal of clinical Nutrition, vol.72 No.1,280s-290s July 2000  6. Корсак Ю.К. по материалам исследований;  а также литературы: Майя Гогулан  “Законы полноценного питания”   7. King JC. Determinants of maternal zinc status during pregnancy. American Journal of Clinical Nutrition. 2000, 71:1334S-1343S.